1312700-28-9Relevant articles and documents
A common approach to pyrrolizidine and indolizidine alkaloids; Formal synthesis of (-)-isoretronecanol, (-)-trachelanthamidine and an approach to the synthesis of (-)-5-epitashiromine and (-)-tashiromine
Reddy, Kotha Kapu Sridhar,Rao, Batchu Venkateswara,Raju, Sagi Satyanarayana
, p. 662 - 668 (2011/07/08)
A common and short stereoselective route is described for the formal synthesis of pyrrolizidine alkaloids, (-)-isoretronecanol and (-)-trachelanthamidine. An approach to the synthesis of indolizidine alkaloids (-)-5-epitashiromine and (-)-tashiromine utilizing ring closing metathesis is also described starting from commercially available and inexpensive l-proline.