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1312784-58-9

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1312784-58-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1312784-58-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,2,7,8 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1312784-58:
(9*1)+(8*3)+(7*1)+(6*2)+(5*7)+(4*8)+(3*4)+(2*5)+(1*8)=149
149 % 10 = 9
So 1312784-58-9 is a valid CAS Registry Number.

1312784-58-9Relevant articles and documents

Preparation method of tert-butyl 1,7-diazaspiro[3.5]nonane-7-carboxylate and oxalate thereof

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Paragraph 0026; 0028-0029; 0037, (2021/08/21)

The invention relates to the field of synthesis of medical intermediates, and particularly discloses tert-butyl 1,7-diazaspiro[3.5]nonane-7-carboxylate and oxalate thereof. The preparation method of tert-butyl 1,7-diazaspiro[3.5]nonane-7-carboxylate comprises the following steps: by taking N-tert-butyloxycarbonyl-4-piperidone, ethyl hydrogen malonate and ammonium acetate as initial raw materials, sequentially carrying out Mannich reaction, reduction reaction, halogenation, cyclization reaction and purification to obtain purified tert-butyl 1,7-diazaspiro[3.5]nonane-7-carboxylate. The preparation method disclosed by the invention is simple to operate and suitable for industrial mass production.

PROTEIN TYROSINE PHOSPHATASE INHIBITORS

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Paragraph 00526, (2020/05/21)

Compounds of Formula la or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative diseases in the view of their ability to inhibit SHP2. Methods of using compounds of Formula I or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

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