1312926-17-2Relevant academic research and scientific papers
Asymmetric neutral amination of nitroolefins catalyzed by chiral bifunctional ammonium salts in water-rich biphasic solvent
Wang, Lijia,Shirakawa, Seiji,Maruoka, Keiji
, p. 5327 - 5330 (2011)
It′s just a phase: Environmentally benign title reaction was achieved under neutral phase-transfer conditions in the presence of 0.05 mol% of a chiral bifunctional ammonium bromide. The importance of bifunctional design of the chiral phase-transfer catalysts (PTC) was clearly shown in the transition-state model of the reaction based on the single-crystal X-ray structure. Bn=benzyl, Boc=tert-butoxycarbonyl.
