1312951-28-2Relevant academic research and scientific papers
Cinchona alkaloid amide catalyzed enantioselective formal [2+2] cycloadditions of allenoates and imines: Synthesis of 2,4-disubstituted azetidines
Denis, Jean-Baptiste,Masson, Geraldine,Retailleau, Pascal,Zhu, Jieping
supporting information; experimental part, p. 5356 - 5360 (2011/06/26)
Mix and go: The quinidine amide 1 catalyzed [2+2] cycloaddition between N-sulfonylimines 2 and alkyl 2,3-butadienoates 3 afforded the R-configured azetidines 4 in excellent yields and enantioselectivities (M.S.=molecular sieve). The S enantiomer was obtained when a quinine amide catalyst, the pseudoenantiomer of 1, was used.
