1312991-15-3

Basic information

• Product Name: 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione
• Synonyms: 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione
• CAS NO: 1312991-15-3
• Molecular Formula: C₂₃H₂₅F₆N₃O₂
• Molecular Weight: 489.4539192
• Mol File: 1312991-15-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione(1312991-15-3)
• EPA Substance Registry System: 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(1-piperidinyl)cyclohexyl]aMino]-3-Cyclobutene-1,2-dione(1312991-15-3)

Safety Data

• Hazardous Substances Data: 1312991-15-3(Hazardous Substances Data)

Upstream product

• 824938-80-9 (1S, 2S)-trans-2-(1-piperidinyl)cyclohexylamine 
• 1223105-85-8 3-(3,5-ditrifluoromethylphenylamino)-4-methoxybutane-3-en-1,2-dione 
• 21436-03-3 (S,S)-1,2-diaminocyclohexane 
• 111-30-8 Glutaraldehyde 

Relevant articles and documents

Chiral squaramide-catalyzed highly enantioselective michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes

A chiral squaramide-organocatalyzed, highly enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes has been developed. This reaction afforded the chiral naphthoquinones in excellent yields (up to 99%) and excellent enantioselectivity (up to 98% ee) under very low catalyst loading (0.25 mol%). This organocatalytic asymmetric Michael addition provides an efficient alternative route toward the synthesis of chiral functionalized naphthoquinones.