1312991-76-6

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Basic information

Product Name: Ro 25-6981 (Maleate)
Synonyms: [R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate salt;1-Piperidinepropanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-, ( αR,βS)-, (2Z)-2-butenedioate (1:1)
CAS NO:1312991-76-6
Molecular Formula: C26H33NO6
Molecular Weight: 455.54332
EINECS: N/A
Product Categories: API
Mol File: 1312991-76-6.mol
Article Data: 0

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: white to beige/
Density: N/A
Refractive Index: N/A
Storage Temp.: 2-8°C
Solubility: H2O: soluble2mg/mL (clear solution, warmed)
CAS DataBase Reference: Ro 25-6981 (Maleate)(CAS DataBase Reference)
NIST Chemistry Reference: Ro 25-6981 (Maleate)(1312991-76-6)
EPA Substance Registry System: Ro 25-6981 (Maleate)(1312991-76-6)

Safety Data

Hazard Codes: Xi,N
Statements: 36/37/38-50
Safety Statements: 26-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1312991-76-6(Hazardous Substances Data)

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Ro 25-6981 Maleate manufacturer/supplier
Cas No: 1312991-76-6
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1 Gram
1000 Metric Ton/Month
Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd
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Zhuozhou Wenxi import and Export Co., Ltd
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Ro 25-6981 Maleate 1312991-76-6
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Taizhou Crene Biotechnology co.ltd
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Ro 25-6981 Maleate
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Ro 25-6981 (Maleate)
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Shanghai Yuanye Bio-Technology Co., Ltd.
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Ro 25-6981 (Maleate)
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Ro 25-6981 Maleate
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Amadis Chemical Co., Ltd.
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25-6981 maleate
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Changzhou Extraordinary Pharmatech co.,LTD
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Ro 25-6981 maleate
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tianjin kailiqi biotechnology co.，ltd
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1312991-76-6 Usage

Biochem/physiol Actions

Ro 25-6981 maleate salt is a potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit with IC50 values of .009 μM for NR2B vs. 52 μM for NR2A subunits. Ro 25-6981 has been shown to have neuroprotectant effects and to reduce inflammatory and neuropathic pain in rodent models.

Check Digit Verification of cas no

The CAS Registry Mumber 1312991-76-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,2,9,9 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1312991-76:
(9*1)+(8*3)+(7*1)+(6*2)+(5*9)+(4*9)+(3*1)+(2*7)+(1*6)=156
156 % 10 = 6
So 1312991-76-6 is a valid CAS Registry Number.

1312991-76-6 Well-known Company Product Price

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(Code)Product description
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Sigma
(SML0495) Ro 25-6981 maleate salt ≥98% (HPLC)
1312991-76-6
SML0495-5MG
1,344.33CNY
Detail

Sigma
(SML0495) Ro 25-6981 maleate salt ≥98% (HPLC)
1312991-76-6
SML0495-25MG
5,446.35CNY
Detail

1312991-76-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name	Ro 25-6981 Maleate

1.2 Other means of identification

Product number	-
Other names	1-Piperidinepropanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

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