1313023-75-4

Upstream product

• 220542-27-8 C₁₅H₁₆N₂O₄S 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1313023-80-1 N-(2-chloro-3-[(2-(2-methylbenzoyl)hydrazono)methyl]-7-phenoxyquinolin-6-yl)formamide 
• 1313023-76-5 [(2-chloro-6-formamido-7-phenoxyquinolin-3-yl)methylene]-N-(4-methoxyphenyl)hydrazinecarbothioamide 
• 1313023-78-7 N-(3-[(2-benzoylhydrazono)methyl]-2-chloro-7-phenoxyquinolin-6-yl)formamide 
• 1313023-79-8 N-(2-chloro-3-[(2-(4-chlorobenzoyl)hydrazono)methyl]-7-phenoxyquinolin-6-yl)formamide 
• 1313023-77-6 N-(2-chloro-3-[(2-(2,4-dinitrophenyl)hydrazono)methyl]-7-phenoxyquinolin-6-yl)formamide 
• 1313023-81-2 N-(2-chloro-3-[(2-(3-nitrobenzoyl)hydrazono)methyl]-7-phenoxyquinolin-6-yl)formamide 
• 1357474-50-0 ethyl 2-((2-chloro-6-formamido-7-phenoxyquinolin-3-yl)(hydroxy)methyl)acrylate 
• 1357474-51-1 methyl 2-((2-chloro-6-formamido-7-phenoxyquinolin-3-yl)(hydroxy)methyl)acrylate 
• 1357474-52-2 N-(2-chloro-3-(2-cyano-1-hydroxyallyl)-7-phenoxyquinolin-6-yl)formamide 
• 1357474-49-7 N-(2-chloro-3-(hydroxy(6-oxocyclohex-1-enyl)methyl)-7-phenoxyquinolin-6-yl)formamide 

Relevant academic research and scientific papers

Design and synthesis of novel cytotoxic agents based on combined framework of quinoline and nimesulide

Functionalization of quinoline aldehydes, derived from nimesulide framework was carried out using Morita-Baylis-Hillman (MBH) chemistry. A number of novel quinoline-based diverse MBH adducts was prepared via the reaction of derivatives of 2-chloroquinolin

Synthesis of novel quinoline analogues of nimesulide: An unusual observation

Reduction of nimesulide followed by treating the N-acyl derivative of resulting arylamine with Vilsmeier-Haack reagent provided novel 2-chloro-3-formylquinoline derivatives. The construction of quinoline ring using Vilsmeier-Haack reagent afforded an unex