1313226-72-0

Basic information

• Product Name: (S)-tert-butyl 2-(benzyloxy)-1-(7-hydroxy-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-5-yl)ethyl carbamate
• Synonyms: (S)-tert-butyl 2-(benzyloxy)-1-(7-hydroxy-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-5-yl)ethyl carbamate
• CAS NO: 1313226-72-0
• Molecular Weight: 443.497
• Mol File: 1313226-72-0.mol

Chemical Properties

• CAS DataBase Reference: (S)-tert-butyl 2-(benzyloxy)-1-(7-hydroxy-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-5-yl)ethyl carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 2-(benzyloxy)-1-(7-hydroxy-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-5-yl)ethyl carbamate(1313226-72-0)
• EPA Substance Registry System: (S)-tert-butyl 2-(benzyloxy)-1-(7-hydroxy-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-5-yl)ethyl carbamate(1313226-72-0)

Safety Data

• Hazardous Substances Data: 1313226-72-0(Hazardous Substances Data)

Upstream product

• 23680-31-1 BOC-O-benzyl-L-serine 
• 1313226-62-8 (S)-tert-butyl 3-(benzyloxy)-1-(1H-imidazol-1-yl)-1-oxopropan-2-ylcarbamate 

Downstream Products

• 1313226-84-4 (R)-tert-butyl 1-(benzyloxymethyl)-4,6-dihydroxy-3-oxoisoindoline-2-carboxylate 

Relevant articles and documents

Conversion of α-amino acids into bioactive o-aminoalkyl resorcylates and related dihydroxyisoindolinones

The synthesis of biologically active o-aminoalkyl resorcylates and related dihydroxyisoindolinones from functionalized α-amino acids without the use of phenolic protection is described. The key aminoalkyl-diketo-dioxinone intermediates were prepared utilizing a crossed Claisen condensation reaction in the presence of diethylzinc. The aromatic unit was constructed via late stage cyclization and aromatization, and subsequent modification provided the novel resorcylates which showed activity against a selection of receptors and kinases, including 5-HT and CDK.