1313358-79-0

Upstream product

• 1313358-61-0 methyl (S)-1-(2-(biphenyl-4-ylmethyl)-2-((2S,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-phenylbutyl)hydrazinyl)-3,3-dioxobutan-2-ylcarbamate 
• 1313358-60-9 (S)-methyl 1-(2-(biphenyl-4-ylmethyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate 
• 1313358-59-6 (S,E)-methyl 1-(2-(biphenyl-4-ylmethylene)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate 
• 3218-36-8 4-Phenylbenzaldehyde 
• 198904-78-8 methyl (S)-(1-hydrazinyl-3,3-dimethyl-1-oxobutan-2-yl)carbamate 
• 198904-77-7 (S)-N'-(2-methoxycarbonylamino-3,3-dimethyl-butyryl)-hydrazinecarboxylic acid tert-butyl ester 
• 162537-11-3 (S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 
• 20859-02-3 L-tert-Leucine 
• 1122-91-4 4-bromo-benzaldehyde 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1313358-35-8 methyl (S)-1-(2-((2S,3S)-3-((1S,3R)-3-acetamido-2,2-dimethylcyclobutanecarboxamido)-2-hydroxy-4-phenylbutyl)-2-(biphenyl-4-ylmethyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate 
• 1313358-37-0 methyl (S)-1-(2-(biphenyl-4-ylmethyl)-2-((2S,3S)-3-((1S,3R)-3-(tert-butoxycarbonylamino)-2,2-dimethylcyclobutanecarboxamido)-2-hydroxy-4-phenylbutyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate 
• 1313358-40-5 methyl (S)-1-(2-((2S,3S)-3-((1R,3S)-3-(benzyloxycarbonylamino)-2,2-dimethylcyclobutanecarboxamido)-2-hydroxy-4-phenylbutyl)-2-(biphenyl-4-ylmethyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate 
• 1313358-36-9 methyl (S)-1-(2-(biphenyl-4-ylmethyl)-2-((2S,3S)-2-hydroxy-3-((1S,3R)-3-(methoxycarbonylamino)-2,2-dimethylcyclobutanecarboxamido)-4-phenylbutyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate 
• 1313358-38-1 methyl (S)-1-(2-(biphenyl-4-ylmethyl)-2-((2S,3S)-2-hydroxy-3-((1R,3S)-3-(methoxycarbonylamino)-2,2-dimethylcyclobutanecarboxamido)-4-phenylbutyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate 
• 1313358-39-2 methyl (S)-1-(2-(biphenyl-4-ylmethyl)-2-((2S,3S)-3-((1R,3S)-3-(tert-butoxycarbonylamino)-2,2-dimethylcyclobutanecarboxamido)-2-hydroxy-4-phenylbutyl)hydrazinyl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate 

Relevant academic research and scientific papers

NOVEL AZA-PEPTIDES CONTAINING 2,2-DISUBSTITUTED CYCLOBUTYL AND/OR SUBSTITUTED ALKOXY BENZYL DERIVATIVES AS ANTIVIRALS

The present invention relates to novel aza-peptides containing 2,2-disubstituted 5 cyclobutyl and/or substituted alkoxy benzyl derivatives of formula (I) and compositions for inhibiting Human Immunodeficiency Virus (HIV) and process for making the compounds.