1313370-79-4

Upstream product

• 106-95-6 allyl bromide 
• 678195-39-6 methyl 1,2-diphenylcycloprop-2-ene-1-carboxylate 
• 22979-35-7 Methyl phenyldiazoacetate 
• 4289-20-7 1-phenyl-4-penten-1-yne 
• 591-50-4 iodobenzene 
• 871-28-3 pent-1-en-4-yne 

Relevant academic research and scientific papers

Dinuclear gold-catalyzed C-H bond functionalization of cyclopropenes

We report an unprecedented C–H bond functionalization of cyclopropenes enabled by dinuclear gold catalysis. Highly selective C–H allylation, alkynylation and halogenation of cyclopropenes with organic halides have been realized. The reaction does not require strong external oxidants and affords access to functionalized cyclopropenes in moderate to good yields. The reductive elimination process to controllably construct C–C or C–X bonds can be tuned by using different dinuclear gold catalysts. [Figure not available: see fulltext.]

Recyclable heterogeneous metal foil-catalyzed cyclopropenation of alkynes and diazoacetates under solvent-free mechanochemical reaction conditions

Silver and copper foil were found to be effective, versatile and selective heterogeneous catalysts for the cyclopropenation of terminal and internal alkynes under mechanochemical reaction conditions. This methodology enables the functionalization of a wide range of terminal or internal alkynes under ambient, aerobic, and solvent-free conditions. Finally, we have demonstrated a unique and versatile one-pot domino Sonogashira-cyclopropenation mechanochemical reaction for the formation of complex cyclopropenes.

Silver triflate-catalyzed cyclopropenation of internal alkynes with donor-/acceptor-substituted diazo compounds

Silver triflate was found to be an efficient catalyst for the cyclopropenation of internal alkynes using donor-/acceptor-substituted diazo compounds as carbenoid precursors. Highly substituted cyclopropenes, which cannot be synthesized directly via rhodium(II)-catalyzed carbenoid chemistry, can now be readily accessed.