1313396-14-3Relevant academic research and scientific papers
Silver-catalyzed synthesis of disubstituted isoxazoles by cyclization of alkynyl oxime ethers
Ueda, Masafumi,Ikeda, Yuki,Sato, Aoi,Ito, Yuta,Kakiuchi, Maiko,Shono, Hiroko,Miyoshi, Tetsuya,Naito, Takeaki,Miyata, Okiko
, p. 4612 - 4615 (2011/07/08)
A facile and practical synthesis of 3,5-disubstituted isoxazoles via a silver-catalyzed cyclization and subsequent protonation of alkynyl oxime ethers has been developed. The methodology was successfully applied to the synthesis of a biologically active i
