1313405-66-1

Basic information

• Product Name: (2E)-3-(2-chloro-8-methylquinolin-3-yl)-1-(3-chlorothien-2-yl)prop-2-en-1-one
• Synonyms: (2E)-3-(2-chloro-8-methylquinolin-3-yl)-1-(3-chlorothien-2-yl)prop-2-en-1-one
• CAS NO: 1313405-66-1
• Molecular Weight: 348.252
• Mol File: 1313405-66-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2E)-3-(2-chloro-8-methylquinolin-3-yl)-1-(3-chlorothien-2-yl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-(2-chloro-8-methylquinolin-3-yl)-1-(3-chlorothien-2-yl)prop-2-en-1-one(1313405-66-1)
• EPA Substance Registry System: (2E)-3-(2-chloro-8-methylquinolin-3-yl)-1-(3-chlorothien-2-yl)prop-2-en-1-one(1313405-66-1)

Safety Data

• Hazardous Substances Data: 1313405-66-1(Hazardous Substances Data)

Upstream product

• 89581-82-8 2-acetyl-3-chlorothiophene 
• 73568-26-0 2-chloro-8-methyl-quinoline-3-carbaldehyde 

Relevant articles and documents

Novel quinolyl-thienyl chalcones and their 2-pyrazoline derivatives with diverse substitution pattern as antileishmanial agents against Leishmania major

A series of twenty-two new pyrazoline derivatives was prepared from quinoline-based chalcones which in turn were synthesized by condensing formylquinolines with diverse acetylthiophenes. The titled compounds were characterized by spectroscopic techniques (NMR, IR and MS) and elemental analysis. All the compounds were screened for antileishmanial activities. Compounds 1e, 1f, 2a, 2c, 2d, 2g, 2k, and 4a were found potentially active antileishmanial agents. Bioassay results show that the type and positions of the substituents seem to be critical for their antileishmanial activities. Springer Science+Business Media, LLC 2011.