1313510-02-9Relevant articles and documents
Tandem metathesis reactions of oxabicyclo[2.2.1]heptenes: Studies on the spirocyclic core of cyclopamine
Oblak, E. Zachary,G-Dayanandan, Narendran,Wright, Dennis L.
, p. 2433 - 2435 (2011)
Chemical equations presented. A rapid approach to the spirocyclic core of cyclopamine was achieved in four steps from 2-pentenyl-furan. A furan Diels-Alder reaction followed by a one-pot dehalogenation/amination sequence provides the oxabicyclic triene that upon treatment with Grubbs catalyst undergoes smooth rearrangement to the tricyclic core.