1313516-92-5 Usage
General Description
(S)-2-chloro-5-Methyl-6a,7,8,9-tetrahydropyrrolo[2,1-h]pteridin-6(5H)-one, also known as leucovorin or citrovorum factor, is a chemical compound that is commonly used as a medication to decrease the toxic effects of methotrexate and certain other chemotherapy drugs. It is a derivative of folic acid and works by providing a source of reduced folate, which helps to prevent the toxic effects of these chemotherapy drugs on healthy tissues. Leucovorin is also used to treat megaloblastic anemia and is being investigated for its potential use in the treatment of alcohol addiction and cognitive impairment. Additionally, it has been found to be effective in the treatment of some types of bacterial and parasitic infections.
Check Digit Verification of cas no
The CAS Registry Mumber 1313516-92-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,3,5,1 and 6 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1313516-92:
(9*1)+(8*3)+(7*1)+(6*3)+(5*5)+(4*1)+(3*6)+(2*9)+(1*2)=125
125 % 10 = 5
So 1313516-92-5 is a valid CAS Registry Number.
1313516-92-5Relevant articles and documents
PTERIDINONES AS INHIBITORS OF POLO - LIKE KINASE
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Page/Page column 59, (2011/07/09)
The present invention provides compounds having a structure according to Formula (I) or a salt or solvate thereof, wherein ring A, X, R1, R2, R3, R4, R5 and R6, are defined herein. The invention further provides pharmaceutical compositions including the compounds of the invention and methods of making and using the compounds and compositions of the invention, e.g., in the treatment and prevention of various disorders, such as Parkinson's disease.
