1313588-10-1

Basic information

• Product Name: C₂₂H₁₈Cl₂F₃N₅O₄
• CAS NO: 1313588-10-1
• Molecular Weight: 544.317
• Mol File: 1313588-10-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₁₈Cl₂F₃N₅O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₁₈Cl₂F₃N₅O₄(1313588-10-1)
• EPA Substance Registry System: C₂₂H₁₈Cl₂F₃N₅O₄(1313588-10-1)

Safety Data

• Hazardous Substances Data: 1313588-10-1(Hazardous Substances Data)

Upstream product

• 88-87-9 4-chloro-2,6-dinitrophenol 
• 2019-34-3 3-(4-chlorophenyl)propanoic acid 
• 1276684-06-0 ethyl 4-chloro-2,6-dinitrophenoxyacetate 
• 1307845-54-0 C₁₄H₁₅ClF₃N₃O 
• 1307845-47-1 C₁₃H₁₃ClF₃N₃ 
• 1307845-40-4 C₁₂H₁₃ClF₃NS 
• 1314664-09-9 C₁₂H₁₃ClF₃NO 
• 870064-73-6 6-chloro-8-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one 

Relevant articles and documents

Optimization of triazoles as novel and potent nonphlorizin SGLT2 inhibitors

Previous efforts have led to the identification of a potent, selective, and nonphlorizin based SGLT2 inhibitor 1. This Letter describes efforts to further optimize the potency, microsomal stability, solubility and pharmacokinetic properties of this series of SGLT2 inhibitors. From these efforts, compounds 28 and 32 have improved solubility and pharmacokinetic properties compared to compound 1.