1313593-77-9Relevant academic research and scientific papers
A convenient synthesis of the core trisaccharide of the N-glycans
Lu, Zhichao,Ding, Ning,Zhang, Wei,Wang, Peng,Li, Yingxia
scheme or table, p. 3320 - 3323 (2011/07/08)
A convenient synthesis of the core trisaccharide of the N-glycans was described. Orthogonal one-pot glycosylation of three monosaccharide building blocks was performed to furnish β-glucosyl chitobiose, which was then transformed to β-mannosyl chitobiose b
Differentiating the 2,3-diols of glucopyranosides by 4,6-O-benzylidene- protected-1,2-D-glucopyranosylorthoesters strategy
Wang, Guangfa,Lu, Zhichao,Ding, Ning,Zhang, Wei,Wang, Peng,Li, Yingxia
experimental part, p. 2368 - 2373 (2011/12/04)
A facile and efficient method to differentiate the 2,3-diols of glucopyranosides based on 1,2-orthoesters strategy was developed. Stable thioglucosides were employed as the starting materials to prepare the corresponding 1,2-orthoesters. When treated with HCl aqueous solution and followed with Et3N, differentiation of the 2,3-diols was efficiently achieved along with the generation of a convertible anomeric hydroxyl group. In addition, an easy and practical method based on NOE was proposed to determine whether the 1,2-orthoesters were endo-type or exo-type.
