1313613-09-0

Basic information

• Product Name: AMZ30
• Synonyms: AMZ30
• CAS NO: 1313613-09-0
• Molecular Formula: C₁₉H₁₂FN₃O₆S₂
• Molecular Weight: 461.4434832
• Mol File: 1313613-09-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: AMZ30(CAS DataBase Reference)
• NIST Chemistry Reference: AMZ30(1313613-09-0)
• EPA Substance Registry System: AMZ30(1313613-09-0)

Safety Data

• Hazardous Substances Data: 1313613-09-0(Hazardous Substances Data)

Usage

Uses

AMZ30 is a potent, selective inhibitor of protein phosphatase methylesterase-1 (PME-1).

Upstream product

• 1313612-96-2 (E)-2-((4-fluorophenyl)sulfonyl)-3-(1H-pyrrol-2-yl)acrylonitrile 
• 121-51-7 3-nitrobenzenesulphonyl chloride 
• 32083-66-2 (4-fluoro-benzenesulphonyl)-acetonitrile 
• 1003-29-8 2-pyrrole aldehyde 

Relevant articles and documents

Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1

The serine hydrolase protein phosphatase methylesterase-1 (PME-1) regulates the methylesterification state of protein phosphatase 2A (PP2A) and has been implicated in cancer and Alzheimer's disease. We recently reported a fluorescence polarization-activit