131364-06-2

Upstream product

• 131364-04-0 C₇₁H₁₃₉NO₁₂Si₄ 
• 131364-05-1 C₇₇H₁₅₃NO₁₂Si₅ 

Downstream Products

• 129873-45-6 (E)-(1R,8S,9R,10S,12R,13R,17S,19S,20R,21S,23R)-13-Allyl-1,10,12-trihydroxy-8-[(E)-2-((1R,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-vinyl]-19,21-dimethoxy-4,9,15,17,23-pentamethyl-7,24-dioxa-4-aza-bicyclo[18.3.1]tetracos-14-ene-2,3,6-trione 
• 129873-36-5 (E)-(1R,8S,9R,10S,13R,17S,19S,20R,21S,23R)-13-Allyl-1,10-dihydroxy-8-[(E)-2-((1R,3R,4R)-4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-vinyl]-19,21-dimethoxy-4,9,15,17,23-pentamethyl-7,24-dioxa-4-aza-bicyclo[18.3.1]tetracos-14-ene-2,3,6,12-tetraone 
• 131364-07-3 C₅₃H₉₅NO₁₂Si₂ 
• 131385-32-5 C₅₃H₉₃NO₁₂Si₂ 

Relevant academic research and scientific papers

Synthesis of the Novel Sarkosine and Proline (FK-525) Analogues of FK-506: Rearrangement of the Allylic Ester System

The novel sarcosine 2 and proline 3 (FK-525) analogues of FK-506 have been synthesized.Allylic rearranged products not observed in the pipecolinic acid series have been isolated from the amino acid formation/macrocyclization step.