1313710-28-9

Basic information

• Product Name: (S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester
• Synonyms: (S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester;(S)-tert-Butyl 2-(2-fluorobenzyl)-3,5-dioxopyrrolidine-1-carboxylate
• CAS NO: 1313710-28-9
• Molecular Formula: C16H18FNO4
• Molecular Weight: 307.3168232
• Mol File: 1313710-28-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 401.0±55.0 °C(Predicted)
• Appearance: /
• Density: 1.311±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.50±1.00(Predicted)
• CAS DataBase Reference: (S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester(1313710-28-9)
• EPA Substance Registry System: (S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester(1313710-28-9)

Safety Data

• Hazardous Substances Data: 1313710-28-9(Hazardous Substances Data)

Usage

Description

(S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester, also known as Fmoc-L-(S)-β-fluoro-phenylglycine, is a chemical compound that serves as an essential building block in the synthesis of peptides and other organic compounds. This amino acid derivative features a fluoro-substituted aromatic ring and a pyrrolidine ring structure, with the tert-butyl ester group enhancing its stability and solubility. Its unique structural and functional properties make it a valuable asset in medicinal chemistry, drug discovery, and various research areas related to organic synthesis.

Uses

Used in Pharmaceutical Industry:
(S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester is used as a key component in the development of novel pharmaceuticals for various therapeutic applications. Its unique structure allows for the creation of peptides with specific properties that can target and treat a wide range of diseases.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester is utilized as a building block for designing and synthesizing new molecules with potential therapeutic effects. Its fluoro-substituted aromatic ring and pyrrolidine ring structure contribute to the development of innovative drug candidates.
Used in Drug Discovery:
(S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester plays a crucial role in drug discovery, as it can be incorporated into the synthesis of new compounds with potential pharmacological activities. Its unique properties enable the development of novel drugs with improved efficacy and selectivity.
Used in Organic Synthesis Research:
In the realm of organic synthesis, (S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester is employed as a versatile building block for creating a diverse range of organic compounds. Its structural and functional characteristics make it an attractive candidate for the synthesis of complex molecules with various applications in chemistry and biology.
Used in Solid-Phase Peptide Synthesis:
(S)-2-(2-Fluoro-benzyl)-3,5-dioxo-pyrrolidine-1-carboxylic acid tert-butyl ester is used as a building block in solid-phase peptide synthesis, allowing for the creation of peptides with specific structural and functional properties. This technique is widely employed in the development of new drugs, vaccines, and other bioactive molecules.