131375-64-9

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 111-29-5 1 ,5-pentanediol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 131375-69-4 5-((4-methoxybenzyl)oxy)pentanal 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 131375-63-8 5-(4-methoxybenzyloxy)-1-pentanol 
• 144152-65-8 (Diethoxy-phosphanyloxy)-acetic acid ethyl ester 

Downstream Products

• 865302-26-7 (2S,3R)-3-[4-(4-methoxyphenylmethoxy)butyl]oxirane-2-carboxaldehyde 
• 865302-25-6 (2R,3R)-3-[4-(4-methoxyphenylmethoxy)butyl]oxirane-2-methanol 
• 865302-35-8 (3R,4R)-(+)-2E-2-[(2R,3R)-2,3-epoxy-7-oxohept-1-enyl]-4-[(1,1-dimethylethyl)diphenylsilyloxy]-3-(2Z-octenyl)-cyclopentanone 
• 865302-34-7 (3R,4R)-(+)-2E-2-[(2R,3R)-2,3-epoxy-7-hydroxyhept-1-enyl]-4-[(1,1-dimethylethyl)diphenylsilyloxy]-3-(2Z-octenyl)-cyclopentanone 
• 865302-36-9 (2R,3R)-3-Z-[(4R,5R)-5-(2Z-octenyl)-2-oxo-4-[(1,1-dimethylethyl)diphenylsilyloxy]cyclopentylidenemethyl]oxirane-2-butanoic acid 
• 865302-33-6 (3R,4R)-(+)-2E-2-[(2R,3R)-2,3-epoxy-7-(4-methoxyphenylmethoxy)hept-1-enyl]-4-[(1,1-dimethylethyl)diphenylsilyloxy]-3-(2Z-octenyl)-cyclopentanone 
• 865302-32-5 (4R,5R)-(+)-2-[(1,1-dimethylethyl)dimethylsilyloxy]-4-[(1,1-dimethylethyl)diphenylsilyloxy]-5-(2Z-octenyl)-α-[(1R,2R)-1,2-epoxy-6-(4-methoxyphenylmethoxy)hexyl]cyclopent-2-enemethanol 
• 865302-38-1 C₆₀H₉₆NO₁₁PSi 
• 853784-92-6 (4R,E)-12-(4-methoxybenzyloxy)-4-(benzyloxy)dodec-7-en-6-ol 
• 131375-66-1 8-p-methoxybenzyloxy-1,1'-dibromoocta-1,3-diene 
• 131375-67-2 8-p-methoxybenzyloxy-(E)-3-octen-1-yne 
• 853785-06-5 (E)-7-(4-methoxybenzyloxy)hept-2-enal 
• 853784-91-5 (E,4R)-12-(4-methoxybenzyloxy)-5-(p-tolylsulfonyl)-4-(benzyloxy)dodec-7-en-6-ol 

Relevant academic research and scientific papers

Total synthesis of the epoxy isoprostane phospholipids PEIPC and PECPC

(Chemical Equation Presented) A total synthesis of the naturally occurring hydroxy ketone PEIPC 1, a compound that plays a role in endothelial activation in atherosclerosis, has been completed via a triply convergent preparation of a protected EI derivative 13 from 3,5-diacetoxycyclopentene 7, pentane-1,5-diol, and vinyllithium, using Sharpless epoxidation and enzymatic resolution as key steps. Final coupling with lyso-PC 16 and silyl group deprotection gave PECPC 2 and PEIPC 1, which showed the same activity as natural PECPC and PEIPC.

Chemoenzymatic total synthesis of the phytotoxic lactone herbarumin III

Asymmetric total synthesis of phytotoxic nonenolide herbarumin III was accomplished by a chemoenzymatic approach. The main highlight of the synthesis was to fix the hydroxyl stereocenters (C7 and C9) by lipase catalyzed irreversible transesterification.

Synthesis of a Novel Acetylenic Ester, Methyl (E)-5-Octadecen-7,9-diynoate

We, herein, report synthesis of methyl ester of (E)-5-octadecen-7,9-diynoic acid, one of the novel acetylenic fatty acids of Paramacrolobium caeruleum root bark with unique biological activity, by coupling synthesized C1 to C8 fragment with 1-decyne.