1313751-06-2

Basic information

• Product Name: C₃₄H₄₂N₆O₇
• Synonyms: C₃₄H₄₂N₆O₇
• CAS NO: 1313751-06-2
• Molecular Weight: 646.743
• Mol File: 1313751-06-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₃₄H₄₂N₆O₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₄H₄₂N₆O₇(1313751-06-2)
• EPA Substance Registry System: C₃₄H₄₂N₆O₇(1313751-06-2)

Safety Data

• Hazardous Substances Data: 1313751-06-2(Hazardous Substances Data)

Upstream product

• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 2425-95-8 2,5-bis(p-aminophenyl)-1,3,4-oxadiazole 

Downstream Products

• 1313751-07-3 C₂₄H₂₆N₆O₃ 
• 1313743-95-1 (2S,2'S)-N,N'-(1.3,4-oxadiazole-2,5-diyldi-4,1-phenylene)bis [1-(cyclopropylacetyl)-2-pyrrolidinecarboxamide] 
• 1313743-91-7 (2S,2'S)-N,N'-(1,3,4-oxadiazole-2,5-diyldi-4,1-phenylene)bis[1-(phenylacetyl)-2-pyrrolidinecarboxamide] 

Relevant articles and documents

HCV NS5A replication complex inhibitors. Part 3

In a recent disclosure,1 we described the discovery of dimeric, prolinamide-based NS5A replication complex inhibitors exhibiting excellent potency towards an HCV genotype 1b replicon. That disclosure dealt with the SAR exploration of the peripheral region of our lead chemotype, and herein is described the SAR uncovered from a complementary effort that focused on the central core region. From this effort, the contribution of the core region to the overall topology of the pharmacophore, primarily vector orientation and planarity, was determined, with a set of analogs exhibiting 50 in a genotype 1b replicon assay.