131379-35-6

Basic information

• Product Name: ETHYL 2'-CYANOBIPHENYL-3-CARBOXYLATE
• Synonyms: ETHYL 2'-CYANOBIPHENYL-3-CARBOXYLATE
• CAS NO: 131379-35-6
• Molecular Formula: C₁₆H₁₃NO₂
• Molecular Weight: 251.28
• Mol File: 131379-35-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ETHYL 2'-CYANOBIPHENYL-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2'-CYANOBIPHENYL-3-CARBOXYLATE(131379-35-6)
• EPA Substance Registry System: ETHYL 2'-CYANOBIPHENYL-3-CARBOXYLATE(131379-35-6)

Safety Data

• Hazardous Substances Data: 131379-35-6(Hazardous Substances Data)

Upstream product

• 1072906-12-7 C₇H₄BrMgN 
• 1219-67-6 N,N-Dimethyl-sulfaminsaeure-<3-aethoxycarbonyl-phenylester> 
• 443296-77-3 ethyl 3-{[(4-methylphenyl)sulfonyl]oxy}benzoate 
• 24398-88-7 ethyl 3-bromobenzoate 
• 2042-37-7 o-cyanobromobenzene 
• 4334-87-6 [3-(ethoxycarbonyl)phenyl]boronic acid 

Relevant articles and documents

Unified Protocol for Fe-Based Catalyzed Biaryl Cross-Couplings between Various Aryl Electrophiles and Aryl Grignard Reagents

The combination of commonly used FeCl3/SIPr with Ti(OEt)4/PhOM enabled a highly general iron-based catalyst system, which could efficiently catalyze the biaryl coupling reaction between various electrophiles (I, Br, Cl, OTs, OCONMe2, OSO2NMe2) and common or functionalized aryl Grignard reagents with high functional group tolerance. Selective couplings of aryl iodides and bromides over the corresponding oxygen-based electrophiles have been achieved, and thus a terphenyl acid intermediate for anidulafungin was conveniently synthesized via an orthogonal coupling strategy.

Highly reactive forms of zinc and reagents thereof

A novel zerovalent zinc species and an organozinc reagent are disclosed. The zerovalent zinc species is directly produced by reaction of a reducing agent on a zinc salt, preferably Zn(CN)2. The organozinc reagent results from the reaction of the zerovalent zinc species and an organic compound having one or more stable anionic leaving groups. These organozinc reagents include a wide spectrum of functional groups in the organic radical, and are useful in a variety of reactions schemes.