13138-73-3

Usage

Uses

Used in Pharmaceutical Industry:
2-(Methoxycarbonyl)-5-nitro-1H-pyrrole is used as a building block for the synthesis of various organic molecules and has potential applications in the development of new drugs and other biologically active compounds. Its unique structure and reactivity make it a valuable component in creating novel pharmaceutical agents.
Used in Organic Synthesis:
2-(Methoxycarbonyl)-5-nitro-1H-pyrrole is used as a key intermediate in the synthesis of a wide range of organic molecules. Its versatility in chemical reactions allows for the creation of diverse compounds with various applications across different industries.

InChI:InChI=1S/C6H6N2O4/c1-12-6(9)4-2-3-5(7-4)8(10)11/h2-3,7H,1H3

Upstream product

• 1193-62-0 methyl Pyrrole-2-carboxylate 
• 53391-41-6 2,2,2-trichloro-1-(5-nitro-1H-pyrrol-2-yl)ethan-1-one 
• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 

Downstream Products

• 869116-29-0 methyl 5-amino-1H-pyrrole-2-carboxylate 
• 13138-75-5 N-methyl-5-nitropyrrole-2-carboxylic acid methyl ester 
• 1190212-18-0 C₁₅H₁₁BrN₂O₂ 
• 1190212-20-4 C₁₇H₁₆N₂O₂ 
• 1190212-17-9 methyl 5-phenyl-7-azaindole-2-carboxylate 
• 1190212-19-1 C₁₆H₁₄N₂O₃ 
• 1190212-21-5 methyl 4,6-dimethyl-7-azaindole-2-carboxylate 

Relevant academic research and scientific papers

New guanidinium-based carboxylate receptors derived from 5-amino-pyrrole-2-carboxylate: Synthesis and first binding studies

The syntheses of two new guanidinium-based carboxylate receptors 2a,b derived from 5-amino pyrrole-2-carboxylate 4 are described. These receptors bind N-acetyl alanine carboxylate and O-acetyl lactate efficiently in aqueous DMSO as could be shown by NMR studies. However, compared to previously reported guanidiniocarbonyl pyrrole receptors 1, the reversal in the direction of the amide group in 2a,b changes both the substrate selectivity (amides are now preferred over esters) and their relative binding affinities. Both effects can be explained based on the calculated complex structure.

Polyaromatic amide compounds and pharmaceutical/cosmetic compositions comprised thereof

Novel pharmaceutically/cosmetically-active polyaromatic amides have the structural formula (I): STR1 wherein Z is a radical --CO--NH-- or --NH--CO--, and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.