1313802-96-8Relevant articles and documents
Using 'biased-privileged' scaffolds to identify lysine methyltransferase inhibitors
Kashyap, Sudhir,Sandler, Joel,Peters, Ulf,Martinez, Eduardo J.,Kapoor, Tarun M.
, p. 2253 - 2260 (2014/04/17)
Methylation of histones by lysine methyltransferases (KMTases) plays important roles in regulating chromatin function. It is also now clear that improper KMTases activity is linked to human diseases, such as cancer. We report an approach that employs drug