131384-80-0 Usage
Chemical compound
1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline is a complex chemical compound, which is not naturally occurring.
Structure
The compound consists of a trichloromethyl group and a tetrahydro-beta-carboline ring system.
Trichloromethyl group
A functional group containing one carbon atom bonded to three chlorine atoms.
Tetrahydro-beta-carboline ring system
A bicyclic compound consisting of a partially hydrogenated carboline ring system.
Research use
It is primarily used in research settings as a precursor to other compounds or as a reference standard for analytical testing.
Potential applications
The compound has potential applications in various fields, such as pharmacology, medicinal chemistry, and the study of neurochemical pathways.
Complex structure and reactivity
Due to its complex structure and potential reactivity, 1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline requires careful handling.
Professional handling
It should only be used by trained professionals in controlled laboratory settings to ensure safety and proper handling.
Check Digit Verification of cas no
The CAS Registry Mumber 131384-80-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,3,8 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 131384-80:
(8*1)+(7*3)+(6*1)+(5*3)+(4*8)+(3*4)+(2*8)+(1*0)=110
110 % 10 = 0
So 131384-80-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H11Cl3N2/c13-12(14,15)11-10-8(5-6-16-11)7-3-1-2-4-9(7)17-10/h1-4,11,16-17H,5-6H2
131384-80-0Relevant academic research and scientific papers
Investigation on Plasma Levels of the Neurotoxin 1-Tricloromethyl-1,2,3,4-tetrahydro-β-carboline after Oral Administration of Chloral Hydrate in Man
Jost, Leuschner,Beuscher, Norbert,Zimmermann, Thomas,Schuerer, Michael,Schulz, Hans-Ulrich,et al.
, p. 1 - 5 (2007/10/03)
Chloral hydrate (CAS 302-17-0) is a widely used hypnotic and sedative agent.It was recently reported in the literature that a neurotoxin, TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline), may be formed in vitro from tryptamine (Ta) and chloral (Clo).Intraperitoneal administration of TaClo led to Parkinson-like symptoms in the rat.Hence, the plasma levels of TaClo were determined at various time-ponts in 18 healthy volunteers in two periods each during a bioavailability study of several chloral hydrate preparations.The limit of quantitation for TaClo was 5 ng/ml.No TaClo could be determined in the plasma of the various volunteers following administration of human therapeutic doses of chloral hydrate.Hence, it is unlikely that TaClo will be formed in man after application of therapeutic doses of chloral hydrate to patients. - Keywords: CAS 302-17-0; Chloraldurat; chloral hydrate; neurotoxin; TaClo; 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline
