1314024-48-0Relevant articles and documents
Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human β3 adrenergic receptor agonists
Morriello, Gregori J.,Wendt, Harvey R.,Bansal, Alka,Salvo, Jerry Di,Feighner, Scott,He, Jiafang,Hurley, Amanda L.,Hreniuk, Donna L.,Salituro, Gino M.,Reddy, Marat Vijay,Galloway, Sheila M.,McGettigan, Katherine K.,Laws, George,McKnight, Crystal,Doss, George A.,Tsou, Nancy N.,Black, Regina M.,Morris, Judy,Ball, Richard G.,Sanfiz, Anthony T.,Streckfuss, Eric,Struthers, Mary,Edmondson, Scott D.
, p. 1865 - 1870 (2011/05/05)
A novel class of human β3-adrenergic receptor agonists was designed in effort to improve selectivity and metabolic stability versus previous disclosed β3-AR agonists. As observed, many of the β3-AR agonists seem to need th