Cas 1314029-55-4,N-((1H-indol-3-yl)(3-nitrophenyl)methyl)-N-methylbenzenamine

1314029-55-4

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Basic information

Product Name: N-((1H-indol-3-yl)(3-nitrophenyl)methyl)-N-methylbenzenamine
Synonyms: N-((1H-indol-3-yl)(3-nitrophenyl)methyl)-N-methylbenzenamine
CAS NO:1314029-55-4
Molecular Formula:
Molecular Weight: 357.412
EINECS: N/A
Product Categories: N/A
Mol File: 1314029-55-4.mol
Article Data: 3

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: N-((1H-indol-3-yl)(3-nitrophenyl)methyl)-N-methylbenzenamine(CAS DataBase Reference)
NIST Chemistry Reference: N-((1H-indol-3-yl)(3-nitrophenyl)methyl)-N-methylbenzenamine(1314029-55-4)
EPA Substance Registry System: N-((1H-indol-3-yl)(3-nitrophenyl)methyl)-N-methylbenzenamine(1314029-55-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1314029-55-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1314029-55-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,4,0,2 and 9 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1314029-55:
(9*1)+(8*3)+(7*1)+(6*4)+(5*0)+(4*2)+(3*9)+(2*5)+(1*5)=114
114 % 10 = 4
So 1314029-55-4 is a valid CAS Registry Number.

1314029-55-4Upstream product

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1314029-55-4Relevant articles and documents

One-pot Solvent Free Synthesis of Some Tert-indolylmethane Amine Derivatives by Fe(HSO4)3 as a Recyclable Catalyst

Rahimizadeh, Mohammad,Eshghi, Hossein,Mokaber-Esfahani, Majid,Gholizadeh, Mostafa

, p. 1265 - 1269 (2014)

Solvent-free synthesis of 3-substituted indole derivatives by a one-pot three-component coupling reaction between aldehyde, N-alkyl aniline and indole by Fe(HSO4)3 catalyzed is described. The noticeable features of this protocol are

3-Substitued indoles: One-pot synthesis and evaluation of anticancer and Src kinase inhibitory activities

Rao, V. Kameshwara,Chhikara, Bhupender S.,Shirazi, Amir Nasrolahi,Tiwari, Rakesh,Parang, Keykavous,Kumar, Anil

experimental part, p. 3511 - 3514 (2011/08/06)

An efficient and economical method was developed for the synthesis of 3-substituted indoles by one-pot three-component coupling reaction of a substituted or unsubstituted benzaldehyde, N-methylaniline, and indole or N-methylindole using Yb(OTf)3-SiO2 as a catalyst. All the synthesized compounds were evaluated for inhibition of cell proliferation of human colon carcinoma (HT-29), human ovarian adenocarcinoma (SK-OV-3), and c-Src kinase activity. The 4-methylphenyl (4o and 4p) and 4-methoxyphenyl (4q) indole derivatives inhibited the cell proliferation of SK-OV-3 and HT-29 cells by 70-77% at a concentration of 50 μM. The unsubstituted phenyl (4d) and 3-nitrophenyl (4l) derivatives showed the inhibition of c-Src kinase with IC50 values of 50.6 and 58.3 μM, respectively.

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