1314093-29-2

Upstream product

• 161835-09-2 1,2-anhydro-3,5,6-tri-O-benzyl-β-D-mannofuranose 

Downstream Products

• 1314093-39-4 (5aS,6S,7R,8aS)-6-benzyloxy-7-((R)-bis(benzyloxy)ethyl)-5a,6,7,8a-tetrahydro-4H-furo[3,2-b][1,2,3]triazolo[1,5-d][1,4]oxazine 
• 1314093-67-8 ethyl 2-((2S,3S,4S,5R)-2-azido-4-benzyloxy-5-((R)-1,2-bis(benzyloxy)ethyl)tetrahydrofuran-3-yloxy)acetate 

Relevant academic research and scientific papers

Ceric ammonium nitrate-catalyzed azidation of 1,2-anhydro sugars: Application in the synthesis of structurally diverse sugar-derived morpholine 1,2,3-triazoles and 1,4-oxazin-2-ones

Azidation of 1,2-anhydro sugars with NaN3 in CH3CN by using a catalytic amount of ceric ammonium nitrate has been accomplished in a regio- and stereoselective manner. Various 1,2-anhydro sugars produced 2-hydroxy-1-azido sugars in good yields which, in turn, were converted to structurally diverse sugar-derived morpholine triazoles and sugar oxazin-2-ones. These sugar derivatives were tested against various commercially available glycosidases, and two of them were found to be active in the micromolar range.