13142-55-7

Basic information

• Product Name: 1-(2,5-dichlorophenyl)urea
• Synonyms: (2,5-dichlorophenyl)urea; N-(2,5-dichlorophenyl)urea
• CAS NO: 13142-55-7
• Molecular Formula: C₇H₆Cl₂N₂O
• Molecular Weight: 205.0413
• Mol File: 13142-55-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 291.5°C at 760 mmHg
• Flash Point: 130.1°C
• Density: 1.534g/cm³
• Vapor Pressure: 0.00194mmHg at 25°C
• Refractive Index: 1.658
• CAS DataBase Reference: 1-(2,5-dichlorophenyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,5-dichlorophenyl)urea(13142-55-7)
• EPA Substance Registry System: 1-(2,5-dichlorophenyl)urea(13142-55-7)

Safety Data

• Hazardous Substances Data: 13142-55-7(Hazardous Substances Data)

Usage

Type of compound

Organic compound

Derived from

Phenylurea

Physical state

White crystalline solid

Solubility

Insoluble in water, soluble in organic solvents

Uses

Pesticide and herbicide

Mechanism of action

Inhibits the enzyme acetolactate synthase in plants

Effect on plants

Disrupts the production of branched-chain amino acids, leading to plant death

Additional use

Intermediate in the synthesis of other organic compounds

Safety precautions

Handle with caution, may be harmful if ingested or inhaled, can cause skin and eye irritation

Upstream product

• 13142-18-2 C₁₄H₁₂Cl₂N₂O 
• 1435-50-3 2-bromo-1,4-dichlorobenzene 
• 18995-49-8 2,5-dichlorophenylcyanamide 
• 590-28-3 potassium cyanate 
• 95-82-9 2,5 dichloroaniline 

Downstream Products

• 1401252-81-0 3-(2,5-dichlorophenylureido)carbonyl-N₁-ethyl-6-hydroxy-4-oxo-pyrido[2,3-h]quinoline 
• 13201-85-9 1,3-bis(2,5-dichlorophenyl)urea 

Relevant articles and documents

Green synthesis, optical properties and catalytic activity of silver nanoparticles in the synthesis of N-monosubstituted ureas in water

We report the green synthesis of silver nanoparticles by using Euphorbia condylocarpa M. bieb root extract for the synthesis of N-monosubstituted ureas in water. UV-visible studies show the absorption band at 420 nm due to surface plasmon resonance (SPR) of the silver nanoparticles. This reveals the reduction of silver ions (Ag+) to silver (Ago) which indicates the formation of silver nanoparticles (Ag NPs). This method has the advantages of high yields, simple methodology and easy work up.

Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives

The optimization of 5,8-disubstituted spirocyclohexane-quinazolinones into potent, selective, soluble PDE7 inhibitors with acceptable in vivo pharmacokinetic parameters is presented.