1314324-00-9 Usage
General Description
CyclopropanaMine, 2-(4-fluorophenyl)-(hydrochloride)(1:1),(1R,2S)- is a chemical compound with the molecular formula C9H11FN?HCl. It is a hydrochloride salt of a cyclopropanamine derivative with a 1:1 stoichiometry. The compound has a 1R,2S stereochemistry and contains a cyclopropyl group, a fluorophenyl group, and a hydrochloride group. It is used as a pharmaceutical intermediate in the synthesis of various drugs and can also exhibit biological activity as a pharmaceutical agent. The compound's specific applications and properties may vary depending on the intended use in chemical or pharmaceutical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 1314324-00-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,4,3,2 and 4 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1314324-00:
(9*1)+(8*3)+(7*1)+(6*4)+(5*3)+(4*2)+(3*4)+(2*0)+(1*0)=99
99 % 10 = 9
So 1314324-00-9 is a valid CAS Registry Number.
1314324-00-9Relevant articles and documents
C-H activation enables a rapid structure-activity relationship study of arylcyclopropyl amines for potent and selective LSD1 inhibitors
Miyamura, Shin,Araki, Misaho,Ota, Yosuke,Itoh, Yukihiro,Yasuda, Shusuke,Masuda, Mitsuharu,Taniguchi, Tomoyuki,Sowa, Yoshihiro,Sakai, Toshiyuki,Suzuki, Takayoshi,Itami, Kenichiro,Yamaguchi, Junichiro
supporting information, p. 8576 - 8585 (2016/09/28)
We describe the structure-activity relationship of various arylcyclopropylamines (ACPAs), which are potent LSD1 inhibitors. More than 45 ACPAs were synthesized rapidly by an unconventional method that we have recently developed, consisting of a C-H borylation and cross-coupling sequence starting from cyclopropylamine. We also generated NCD38 derivatives, which are known as LSD1 selective inhibitors, and discovered a more effective inhibitor compared to the original NCD38.
