1314378-16-9 Usage
Description
alpha, oMega-DisucciniMidyl diethylene glycol is a chemical compound that consists of a diethylene glycol backbone with two succinimide groups attached to the alpha and omega positions. It is a versatile reagent used for the conjugation of various molecules, enhancing their solubility and stability in aqueous media.
Uses
Used in Pharmaceutical Industry:
alpha, oMega-DisucciniMidyl diethylene glycol is used as a PEGylation agent for the modification of therapeutic proteins and peptides. The PEGylation process improves the solubility, stability, and circulation time of these biomolecules, reducing their immunogenicity and increasing their therapeutic efficacy.
Used in Bioconjugation:
alpha, oMega-DisucciniMidyl diethylene glycol is used as a crosslinking agent for the conjugation of amine-containing molecules, such as proteins, peptides, and oligonucleotides. The succinimide groups react with primary amines to form stable amide bonds, allowing for the attachment of multiple functional groups to a single molecule.
Used in Drug Delivery Systems:
alpha, oMega-DisucciniMidyl diethylene glycol is used as a component in the design of drug delivery systems, such as nanoparticles and hydrogels. The hydrophilic PEG spacer enhances the solubility and biocompatibility of these systems, while the succinimide groups allow for the covalent attachment of drug molecules or targeting ligands.
Used in Diagnostic Imaging:
alpha, oMega-DisucciniMidyl diethylene glycol is used as a contrast agent in medical imaging techniques, such as magnetic resonance imaging (MRI) and computed tomography (CT). The PEGylation of imaging agents improves their solubility, circulation time, and targeting ability, leading to enhanced image contrast and diagnostic accuracy.
Used in Biosensor Development:
alpha, oMega-DisucciniMidyl diethylene glycol is used in the development of biosensors for the detection of various analytes, such as proteins, nucleic acids, and small molecules. The PEGylation of sensor components improves their stability, sensitivity, and selectivity, enabling rapid and accurate detection of target molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1314378-16-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,4,3,7 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1314378-16:
(9*1)+(8*3)+(7*1)+(6*4)+(5*3)+(4*7)+(3*8)+(2*1)+(1*6)=139
139 % 10 = 9
So 1314378-16-9 is a valid CAS Registry Number.
