1314564-52-7Relevant academic research and scientific papers
Iodine catalysed synthesis of unsymmetrical benzylic ethers by direct cross-coupling of alcohols
Kharrngi, Balamphrang,Basumatary, Grace,Bez, Ghanashyam
, (2021)
Although symmetrical ethers can be synthesized easily from alcohols, synthesis of unsymmetrical ethers by dehydrative cross-coupling of alcohols is still a challenge. While dehydrative cross-coupling is environmentally appealing due to formation of water as the only byproduct, the chances for formation of symmetrical ethers always exist. The existing transition metal based methods give good selectivity, but the catalyst are costly and not readily available. Here, we present a simple, readily available, and cost-effective catalyst in the form of molecular iodine which catalyzes a highly selective cross-coupling of benzylic alcohols with benzyl, alkyl, and aryl alcohols to give their corresponding unsymmetrical ethers in good to excellent yield.
Cross-coupling of mesylated phenol derivatives with potassium alkoxymethyltrifluoroborates
Molander, Gary A.,Beaumard, Floriane
, p. 3948 - 3951 (2011/09/16)
Cross-coupling of mesylated phenol derivatives with various potassium alkoxymethyltrifluoroborates has been achieved. The corresponding aryl and heteroaryl alkoxymethyl compounds have been obtained with equal facility with both electron-rich and electron-poor substituents on the activated alcohol.
