1314595-90-8

Basic information

• Product Name: N-(2-iodo-4-methoxylphenyl)-4-methylbenzenesulfonamide
• Synonyms: N-(2-iodo-4-methoxylphenyl)-4-methylbenzenesulfonamide
• CAS NO: 1314595-90-8
• Molecular Weight: 403.241
• Mol File: 1314595-90-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: N-(2-iodo-4-methoxylphenyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-iodo-4-methoxylphenyl)-4-methylbenzenesulfonamide(1314595-90-8)
• EPA Substance Registry System: N-(2-iodo-4-methoxylphenyl)-4-methylbenzenesulfonamide(1314595-90-8)

Safety Data

• Hazardous Substances Data: 1314595-90-8(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 191348-14-8 2-iodo-4-methoxylaniline 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 1449580-47-5 C₁₇H₁₆INO₃S 
• 1225275-00-2 N-[2-(1,1-difluorohex-1-en-2-yl)-4-methoxyphenyl]-4-methylbenzenesulfonamide 
• 910896-38-7 5-methoxy-2-phenyl-1-(p-toluenesulfonyl)indole 
• 1591916-49-2 C₁₇H₁₆INO₃S 

Relevant articles and documents

Asymmetric Counteranion Directed Catalytic Heck/Tsuji-Trost Annulation of Aryl Iodides and 1,3-Dienes

A chiral anion-mediated asymmetric Heck/Tsuji-Trost reaction of aryl iodides and 1,3-dienes is presented. Chiral indoline derivatives could be afforded with remarkably higher yields and enantioselectivities than our previous chiral ligand-based method. Silver carbonate is employed as both base and halide scavenger to ensure fast and recyclable exchange of the catalytic amount of chiral anions. Fast salt metathesis, as well as the acceleration effect of the chiral anion, could both benefit the stereocontrol of the reaction.

Nickel-Catalyzed trans-Carboamination across Internal Alkynes to Access Multifunctionalized Indoles

A Ni-catalyzed reaction was developed for the synthesis of multifunctionalized indoles. The reaction proceeded through oxidative cyclization of the Ni(0)/P^N complex with an enyne system, 2-alkynyl anilinoacrylate, to provide a nickelacycle intermediate. The trans-carboamination around the internal alkyne was achieved by syn/anti-rotation of the Ni-carbenoid intermediate formed by C-N bond cleavage of the nickelacycle, and 3-alkenylated indoles were formed by C-N bond-forming reductive elimination. Notably, the synthesized indoles could be successfully transformed to functionalized carbazoles.

Parallel strategies for the synthesis of annulated pyrido[3,4-b]indoles via Rh(I)- and Pd(0)-catalyzed cyclotrimerization

Two different pathways for the synthesis of annulated pyrido[3,4-b]indoles are reported using metal-catalyzed cyclotrimerization reactions. A stepwise process using Rh(I)-catalysis in the final step of the synthesis and a multicomponent, tandem catalytic