1314745-52-2Relevant academic research and scientific papers
Polyfunctional Imidazoles: II.* synthesis and reactions with nucleophilic reagents of 1-substituted 2,4-Dichloro-1H-imidazole-5-carbaldehydes
Chornous,Grozav,Rusanov,Nesterenko,Vovk
, p. 702 - 709 (2011)
1-Alkyl(aryl)imidazolidine-2,4-diones reacted with Vilsmeier-Haack reagent affording 1-alkyl(aryl)-2,4-dichloro-1H-imidazole-5-carbaldehydes whose reactions with sodium azide, sodium alkoholates, with phenols, thiols, and secondary cycloalkylamines led to the substitution of chlorine in the position 2 of the imidazole ring. The reaction with primary amines resulted in the condensation products at the aldehyde group. Pleiades Publishing, Ltd., 2011.
