1314766-44-3

Upstream product

• 100-44-7 benzyl chloride 
• 115822-48-5 (S,S)-2-<(tert-butoxycarbonyl)amino>-3-hydroxy-2-N,3-O-isopropylidene-1(1,3-thiazol-2-yl)propan-1-ol 
• 1314766-43-2 (2S,3S)-3-O-benzyl-2-tert-butyloxycarbonylamino-3-(thiazol-2-yl)-1,3-propanediol 
• 118605-55-3 (2,3,4,6-tetra-O-pivaloyl-α-D-galactopyranoside)-1-trichloroacetimidate 

Downstream Products

• 1314766-46-5 (2S,3S)-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-3-(thiazol-2-yl)-1,3-propanediol 
• 1314766-47-6 C₅₄H₈₉NO₁₃ 
• 1314766-48-7 (2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-icosanediol 
• 1314766-49-8 (2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-nonadecanediol 
• 1314766-50-1 (2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-heptadecanediol 
• 1314766-51-2 (2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-tridecanediol 
• 1314766-52-3 (2S,3R)-5-aza-3-O-benzyl-2-heptadecanoylamino-1-O-(2,3,4,6-tetra-O-pivaloyl-β-D-galactopyranosyl)-1,3-decanediol 
• 1314766-53-4 (2S,3R)-5-aza-2-heptadecanoylamino-1-O-(β-D-galactopyranosyl)-1,3-icosanediol 
• 1314766-55-6 (2S,3R)-5-aza-2-heptadecanoylamino-1-O-(β-D-galactopyranosyl)-1,3-heptadecanediol 
• 1314766-56-7 C₄₁H₈₂N₂O₈ 
• 1314766-57-8 C₃₅H₇₀N₂O₈ 
• 1314766-58-9 C₃₂H₆₄N₂O₈ 

Relevant academic research and scientific papers

Novel and convergent synthesis of modified glycosphingolipids, galactosyl-5-aza-sphinganines, by a diversity-oriented method

The stereocontrolled synthesis of β-galactosyl-5-aza-sphinganines was accomplished with high efficiency by a novel and convergent strategy. The truncated β-galactosphinganine 5 was easily acylated with different long chains. Moreover, the simple conversion of thiazole to formyl enabled 5-aza-alkylchains to be introduced via an amino-reduction reaction. The overall yield for the synthesis of β-galacto-5-aza-sphinganines 9 and 13 was about 30-35% starting from 5. Preliminary results concerning the β- transgalactosylation of a truncated sphinganine catalyzed by galactosidases are also presented and discussed.