131480-08-5Relevant academic research and scientific papers
CeCl3.7H2O-SiO2 catalyzed ultrasonicated solvent-free synthesis of carbamoyl/carbamothioyl phosphonates and antimicrobial activity evaluation
Rao, Devineni Subba,Madhava, Golla,Rasheed, Syed,Thahir Basha, Shaik,Devamma, Mundla Naga Lakshmi,Raju, Chamarthi Naga
, p. 574 - 584 (2015/05/20)
an expeditious and green method has been developed for the synthesis of a series of PC bond derivatives, diethyl substituted phenylcarbamoylphosphonates 6(a-e)/phenylcarbamothioylphosphonates 7(a-f) in high yields via simple addition reaction of isocyanates/isothiocyanates with diethyl phosphite in the presence of silica supported Lewis acid catalyst, SiO2-CeCl3.7H2O under solvent-free and sonication conditions. The advantages of this method are high yields, avoiding of harmful solvents, operational simplicity, shorter reaction time, and recoverability and recyclability of the catalyst. Antimicrobial activity was assayed for the title compounds, whereas the compounds 6c, 7b, and 7e against bacteria, and 6a, 7b, 7c, and 7e against fungi exhibited potential growth of inhibition.
THE VICARIOUS INTRAMOLECULAR SUBSTITUTION REACTIONS. I. SYNTHESIS OF CONDENSED INDOLIZINES BASED ON 2-QUINOXALYLACETONITRILES
Litvinenko, S. V.,Volovenko, Yu. M.,Babichev, F. S.
, p. 307 - 312 (2007/10/02)
The interaction of α-substituted 2-(3-chloro)quinoxalylacetonitriles with azines to give condensed indolizinoquinoxalines has been studied. A mechanism for the reaction has been proposed which includes an intramolecular vicarious substitution of hydrogen in the azolium salt nucleus. The limits of utility of the reaction have been determined and some chemical properties of the compounds synthesized have been studied.
Synthesis of organophosphorus compounds via silyl esters of phosphorous acids
Afarinkia, Kamyar,Rees, Charles W.,Cadogan, John I. G.
, p. 7175 - 7196 (2007/10/02)
The addition of trimethylsilyloxy phosphorus (III)derivatives generated in situ to imines at room temperature provides a mild selective and high yielding route to α-aminoalkylphosphorate and α-aminoalkylphenylphosphinate esters. Isocyanates and carbodiimides react similarly to give phosphonoureas and phosphonoguarnidines respectively aldehydes and ketones are much less reactive and cyanides are inert.
