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1314804-41-5

C15H16N2O4S is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1314804-41-5 Structure

  • Basic information

    1. Product Name: C15H16N2O4S
    2. Synonyms:
    3. CAS NO:1314804-41-5
    4. Molecular Formula:
    5. Molecular Weight: 320.369
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1314804-41-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C15H16N2O4S(CAS DataBase Reference)
    10. NIST Chemistry Reference: C15H16N2O4S(1314804-41-5)
    11. EPA Substance Registry System: C15H16N2O4S(1314804-41-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1314804-41-5(Hazardous Substances Data)

1314804-41-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1314804-41-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,4,8,0 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1314804-41:
(9*1)+(8*3)+(7*1)+(6*4)+(5*8)+(4*0)+(3*4)+(2*4)+(1*1)=125
125 % 10 = 5
So 1314804-41-5 is a valid CAS Registry Number.

1314804-41-5Relevant articles and documents

Substituted N-aryl-6-pyrimidinones: A new class of potent, selective, and orally active p38 MAP kinase inhibitors

Devadas, Balekudru,Selness, Shaun R.,Xing, Li,Madsen, Heather M.,Marrufo, Laura D.,Shieh, Huey,Messing, Dean M.,Yang, Jerry Z.,Morgan, Heidi M.,Anderson, Gary D.,Webb, Elizabeth G.,Zhang, Jian,Devraj, Rajesh V.,Monahan, Joseph B.

, p. 3856 - 3860 (2011/08/06)

A novel series of highly potent and selective p38 MAP kinase inhibitors was developed originating from a substituted N-aryl-6-pyrimidinone scaffold. SAR studies coupled with in vivo evaluations in rat arthritis model culminated in the identification of 10 with excellent oral efficacy. Compound 10 exhibited a significantly enhanced dissolution rate compared to 1, translating to a high oral bioavailability (>90%) in rat. In animal studies 10 inhibited LPS-stimulated production of tumor necrosis factor-α in a dose-dependent manner and demonstrated robust efficacy comparable to dexamethasone in a rat streptococcal cell wall-induced arthritis model.

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