131483-93-7

Upstream product

• 114916-44-8 cis-1-benzyl-1,2,3,4,4a,5,10,10a-octahydro-9-methoxybenzoquinoline 
• 100-44-7 benzyl chloride 
• 340966-75-8 9-Methoxy-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]quinoline 

Downstream Products

• 131484-04-3 (-)-(4aR,10aS)-1-benzyl-1,2,3,4,4a,5,10,10a-octahydro-9-methoxybenzoquinoline 
• 131563-43-4 (+)-(4aS,10aS)-1-benzyl-1,2,3,4,4a,5,10,10a-octahydro-9-methoxybenzoquinoline hydrochloride 
• 131563-44-5 (-)-(4aR,10aR)-1-benzyl-1,2,3,4,4a,5,10,10a-octahydro-9-methoxybenzoquinoline hydrochloride 

Relevant academic research and scientific papers

A 3-D model for 5-HT(1A)-receptor agonists based on stereoselective methyl-substituted and conformationally restricted analogues of 8-hydroxy-2-(dipropylamino)tetralin

The enantiomers of cis- and trans-1,2,3,4,4a,5,10,10a-octahydro-9-hydroxy-1-propylbenzo[g] quinolines (10 and 11, respectively) and the enantiomers of trans-1,2,3,4,4a,5,6,10b-octahydro-10-hydroxy-4-propylbenzo[f] quinoline (12) have been synthesized and

STEROSELECTIVE SYNTHESIS OF METHOXY SUBSTITUTED 1,2,3,4,4a,5,10,10a-OCTAHYDROBENZOQUINOLINES

The preparation of the cis- and trans-isomers of 6- and 9-methoxy-1,2,3,4,4a,5,10,10a,-octahydrobenzo-quinoline is reported.The syntheses involved reductions of cyclic iminium chlorides, which afforded the diastereomers conveniently and in good yields.