1314875-01-8Relevant academic research and scientific papers
Anilinotriazoles as potent gamma secretase modulators
Velter, Adriana I.,Bischoff, Franois P.,Berthelot, Didier,De Cleyn, Michel,Oehlrich, Daniel,Jaroskova, Libuse,Macdonald, Gregor,Minne, Garrett,Pieters, Serge,Rombouts, Frederik,Van Brandt, Sven,Van Roosbroeck, Yves,Surkyn, Michel,Trabanco, Andrs A.,Tresadern, Gary,Wu, Tongfei,Borghys, Herman,Mercken, Marc,Masungi, Chantal,Gijsen, Harrie
, p. 5805 - 5813 (2015/01/08)
The design and synthesis of a novel series of potent gamma secretase modulators is described. Exploration of various spacer groups between the triazole ring and the aromatic appendix in 2 has led to anilinotriazole 28, which combined high in vitro and in
NOVEL SUBSTITUTED TRIAZOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS
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Page/Page column 59-60, (2011/08/04)
The present invention is concerned with novel substituted triazole derivatives of Formula (I) wherein Het1, R1, R2, A1, A2, A3, A4, L1, and L2 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma sec
