1314875-83-6Relevant academic research and scientific papers
Anti-HIV-1 activity of a tripodal receptor that recognizes mannose oligomers
Rivero-Buceta, Eva,Carrero, Paula,Casanova, Elena,Doyagüez, Elisa G.,Madrona, Andrés,Quesada, Ernesto,Peréz-Pérez, María Jesús,Mateos, Raquel,Bravo, Laura,Mathys, Leen,Noppen, Sam,Kiselev, Evgeny,Marchand, Christophe,Pommier, Yves,Liekens, Sandra,Balzarini, Jan,Camarasa, María José,San-Félix, Ana
, p. 132 - 143 (2015/11/16)
The glycoprotein gp120 of the HIV-1 viral envelope has a high content in mannose residues, particularly α-1,2-mannose oligomers. Compounds that interact with these high-mannose type glycans may disturb the interaction between gp120 and its (co)receptors a
