13149-87-6

Basic information

• Product Name: C18E8
• Synonyms: C18E8;OCTAETHYLENE GLYCOL MONOOCTADECYL ETHER;OCTADECYL OCTAETHYLENE GLYCOL ETHER;OCTADECYLOCTAGLYCOL;POLYETHYLENE GLYCOL (50) MONOSTEARATE;POLYOXYL 50 STEARATE;POLYOXYETHYLENE 8 STEARATE;MYRJ(TM) 53
• CAS NO: 13149-87-6
• Molecular Formula: C34H70O9
• Molecular Weight: 622.91
• Mol File: 13149-87-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 47-49 °C
• Boiling Point: 649.2°Cat760mmHg
• Flash Point: 346.4°C
• Appearance: /
• Density: 0.976g/cm³
• Vapor Pressure: 1.34E-19mmHg at 25°C
• Refractive Index: 1.46
• CAS DataBase Reference: C18E8(CAS DataBase Reference)
• NIST Chemistry Reference: C18E8(13149-87-6)
• EPA Substance Registry System: C18E8(13149-87-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-24/25
• WGK Germany: 1
• RTECS: MD0907300
• Hazardous Substances Data: 13149-87-6(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 13149-87-6 differently. You can refer to the following data:
1. Pharmaceutic aid (surfactant); pharmaceutic aid (emulsifying agent).
2. Octaethylene Glycol Monooctadecyl Ether is a detergent.

Brand name

Myrj 53 (ICI Americas).

InChI:InChI=1/C34H70O9/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-36-21-23-38-25-27-40-29-31-42-33-34-43-32-30-41-28-26-39-24-22-37-20-18-35/h35H,2-34H2,1H3

Relevant articles and documents

Combinatorial synthesis of PEG oligomer libraries

A simple chain-extending approach was established for the scale-up of the monoprotected monodisperse PEG diol materials. Reactions of THP-(OCH2CH2)n—OMs (n=4, 8, 12) with a large excess of commercially available H—(OCH2CH2)n—OH (n=1-4) under basic conditions led to THP-(OCH2CH2)n—OH (n=5-15). Similarly, Me-(OCH2CH2)n—OH (n=4-11, 13) were prepared from Me-(OCH2CH2)n—OMs (n=3, 7, 11). For the chain elongation steps, 40-80% yields were achieved through extraction purification. PEG oligomer libraries I and II were generated in 50-95% overall yields by alkylation or acylation of THP-(OCH2CH2)n—OH (n=1-15) followed by deprotection. Alkylation of Me-(OCH2CH2)n—OH (n=1-11, 13) with X—(CH2)m—CO2R (X=Br or OMs) and subsequent hydrolysis led to PEG oligomer library III in 30-60% overall yields. Combinatorial purification techniques were adapted to the larger-scale library synthesis. A total of 498 compounds, each with a weight of 2-5 g and a minimum purity of 90%, were synthesized.