1314905-61-7

Basic information

• Product Name: (3-chloro-2-fluorophenyl)methanesulfonyl chloride
• Synonyms: (3-chloro-2-fluorophenyl)methanesulfonyl chloride
• CAS NO: 1314905-61-7
• Molecular Formula: C7H5Cl2FO2S
• Molecular Weight: 243.08
• Mol File: 1314905-61-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-chloro-2-fluorophenyl)methanesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (3-chloro-2-fluorophenyl)methanesulfonyl chloride(1314905-61-7)
• EPA Substance Registry System: (3-chloro-2-fluorophenyl)methanesulfonyl chloride(1314905-61-7)

Safety Data

• Hazardous Substances Data: 1314905-61-7(Hazardous Substances Data)

Upstream product

• 876384-47-3 3-chloro-2-fluorobenzyl chloride 

Relevant articles and documents

Palladium-Catalyzed Remote meta-Selective C-H Bond Silylation and Germanylation

Selective meta-C-H activation of arenes to date has met with a limited number of functionalizations. Expanding the horizon of meta-C-H functionalization, herein we disclose an unprecedented meta-silylation and -germanylation protocol by employing a simple nitrile-based directing template. Longer linkers between the target site and the directing template were successfully explored for meta-silylation (sp2-? and sp2-ζ). Additionally, synthetic utility was demonstrated with several postsynthetic elaborations and with a formal synthesis of TAC101, a promising drug for the treatment of lung cancer.