1314906-69-8Relevant academic research and scientific papers
Biocatalytic access to α,α-dialkyl-α-amino acids by a mechanism-based approach
Fesko, Kateryna,Uhl, Michael,Steinreiber, Johannes,Gruber, Karl,Griengl, Herfried
, p. 121 - 124 (2010)
(figure presented) New donors - new products: Threonine aldolases (L-TA, D-TA) have now been found to accept donors other than glycine. In a simple asymmetric biocatalytic aldol reaction alanine, serine, and cysteine reacted with a range of simple acceptor aldehydes to yielded α-substituted serine derivatives (see scheme; PLP=pyridoxal phosphate).
