1314970-23-4Relevant academic research and scientific papers
Discovery of indoline derivatives that inhibit esophageal squamous cell carcinoma growth by Noxa mediated apoptosis
Fu, Dong-Jun,Li, Miaomiao,Zhang, Sai-Yang,Li, Jiang-Feng,Sha, Beibei,Wang, Longhao,Zhang, Yan-Bing,Chen, Ping,Hu, Tao
supporting information, (2019/08/27)
A series of novel indoline derivatives were synthesized and evaluated for antiproliferative activity against four selected cancer cell lines (Hela, A549, HepG2 and KYSE30). Among them, compound 20 displayed the potent inhibition activity against esophagea
CH activation and CH2 double activation of indolines by radical translocation: Understanding the chemistry of the indolinyl radical
Harrowven, David C.,Stenning, Kerri J.,Whiting, Sally,Thompson, Toby,Walton, Robert
experimental part, p. 4882 - 4885 (2011/08/05)
CH activation and CH2 double activation of indolines at C2 may be achieved efficiently through radical translocation. The fate of the C2 indolinyl radical is dictated by the substitution at C3. Fragmentation, cyclisation and tandem cyclisation reactions leading to indole, azaheterocycle and azapropellane formation, respectively, are reported. The Royal Society of Chemistry 2011.
