1315020-11-1

Basic information

• Product Name: (5R)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one
• CAS NO: 1315020-11-1
• Molecular Weight: 131.131
• Mol File: 1315020-11-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (5R)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one(1315020-11-1)
• EPA Substance Registry System: (5R)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one(1315020-11-1)

Safety Data

• Hazardous Substances Data: 1315020-11-1(Hazardous Substances Data)

Usage

General Description

(5R)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one is a chemical compound with a molecular formula of C5H9NO3. It is classified as an oxazolidinone, which is a class of heterocyclic organic compounds. The compound features a five-membered ring containing oxygen and nitrogen atoms, with a hydroxymethyl group and a methyl group attached to the ring. This chemical is typically used as a building block for the synthesis of pharmaceuticals and agrochemicals, and it has shown potential biological activity in certain applications. Additionally, it has been studied as a potential drug candidate for various therapeutic indications due to its unique structural properties. Overall, (5R)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one is an important and versatile compound with diverse potential applications in drug discovery and development.

Upstream product

• 19213-72-0 ethyl 1-imidazolecarboxylate 
• 40137-22-2 3-methylamino-propane-1,2-diol 
• 254436-44-7 (2R)-3-(methylamino)propane-1,2-diol 
• 105-58-8 Diethyl carbonate 
• 637343-84-1 (S)-3-methyl-5-(trityloxymethyl)oxazolidin-2-one 

Downstream Products

• 637343-93-2 N-methil-5-aminomethyl-2-oxazolidinone 

Relevant articles and documents

Ethyl imidazole-1-carboxylate (EImC) as a carbonylating agent: Efficient synthesis of oxazolidin-2-ones from amino alcohols

Various substituted oxazolidin-2-ones were synthesized from the corresponding amino alcohols using ethyl imidazole- 1-carboxylate (EImC). Highly substituted and sterically hindered amino alcohols and amino alcohols having a free hydroxy group were cyclized to oxazolidin-2-ones efficiently. This method is simple and produces oxazolidin-2-ones in very good yield.

TRI-CYCLE COMPOUND AND APPLICATIONS THEREOF

Disclosed in the present invention are a compound represented by formula (I), a tautomer thereof or a pharmaceutically acceptable salt, and applications thereof in the preparation of drugs for treating HBV-related diseases.

1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES

The present invention relates to 1,3-thiazol-2-yl substituted benzamide compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neurogenic disorder, as a sole agent or in combination with other active ingredients.