1315050-97-5Relevant academic research and scientific papers
Two asymmetric syntheses of AMG 221, an inhibitor of 11β- hydroxysteroid dehydrogenase type 1
Caille, Seb,Cui, Sheng,Hwang, Tsang-Lin,Wang, Xiang,Faul, Margaret M.
experimental part, p. 3833 - 3842 (2009/11/30)
(Chemical Equation Presented) Two asymmetric syntheses of AMG 221 (2), an inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) discovered in our laboratories, are reported. One of the syntheses utilizes chiral trimethylsilyl cyanohydrin 12 as s
