131507-85-2

Upstream product

• 103576-53-0 methyl 30-O-acetyltetronasin 
• 131507-82-9 Acetic acid (E)-2-((2R,3R,6S)-6-dimethoxymethyl-3-methyl-tetrahydro-pyran-2-yl)-3-{(1S,2S,3R)-2-[(S)-2-(4-methoxy-2-oxo-2,5-dihydro-furan-3-yl)-1-methyl-2-oxo-ethyl]-3-methyl-cyclohexyl}-allyl ester 
• 131507-84-1 Acetic acid 2-((2R,3R,6S)-6-dimethoxymethyl-3-methyl-tetrahydro-pyran-2-yl)-2-oxo-ethyl ester 

Downstream Products

• 131507-76-1 2-(tert-Butyl-diphenyl-silanyloxy)-1-((2R,3R,6S)-6-{(E)-(S)-3-[(2R,3S,5R)-5-((S)-1-methoxy-ethyl)-3-methyl-tetrahydro-furan-2-yl]-but-1-enyl}-3-methyl-tetrahydro-pyran-2-yl)-ethanone 

Relevant academic research and scientific papers

Synthesis of the C12-C26 fragment of the acyltetronic acid ionophore antibiotic tetronasin (ici 139603)

Preparation of a central tetrahydropyran portion (2) of the antibiotic tetronasin (1) was achieved using an all-in-one epoxidation / cyclization modification of the Sharpless reaction. Further manipulation and coupling reactions afforded the C12-C26 fragm