131523-99-4

Upstream product

• 5123-55-7 Nα-phthaloyl-L-phenylalanine 
• 32150-91-7 phthaloyl-L-phenylalanyl chloride 

Downstream Products

• 1352720-59-2 (S)-2-(1,3-dioxoisoindolin-2-yl)-N-((R)-2-hydroxy-2-(4-methoxyphenyl)ethyl)-3-phenylpropanamide 
• 1352720-49-0 (S)-2-(1,3-dioxoisoindolin-2-yl)-3-phenyl-N-(2,4,6-trimethylbenzoyloxy)propanamide 

Relevant academic research and scientific papers

Intermolecular, Branch-Selective, and Redox-Neutral Cp*IrIII-Catalyzed Allylic C?H Amidation

Herein, we report the redox-neutral, intermolecular, and highly branch-selective amidation of allylic C?H bonds enabled by Cp*IrIII catalysis. A variety of readily available carboxylic acids were converted into the corresponding dioxazolones and efficiently coupled with terminal and internal olefins in high yields and selectivities. Mechanistic investigations support the formation of a nucleophilic IrIII–allyl intermediate rather than the direct insertion of an Ir–nitrenoid species into the allylic C?H bond.

Amino acid-based reoxidants for aminohydroxylation: Application to the construction of amino acid-amino alcohol conjugates

A viable nitrogen source for the aminohydroxylation reaction of terminal alkenes: By adding a N-O based reoxidant onto an amino acid acyl carbon atom, compounds were obtained that facilitated catalytic turnover and also promoted the conjugation of an amino acid with an alkene. High levels of regioselectivity were observed, as well as good stereoselectivity induced by catalytic amounts of a chiral ligand.