13153-63-4

Basic information

• Product Name: 6-methylsulfanyl-9-(oxan-2-yl)purine
• Synonyms: 6-methylsulfanyl-9-(oxan-2-yl)purine
• CAS NO: 13153-63-4
• Molecular Formula: C₁₁H₁₄N₄OS
• Molecular Weight: 250.32
• Mol File: 13153-63-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 461.4°Cat760mmHg
• Flash Point: 232.8°C
• Appearance: /
• Density: 1.47g/cm³
• Vapor Pressure: 1.08E-08mmHg at 25°C
• Refractive Index: 1.732
• PKA: 1.35±0.10(Predicted)
• CAS DataBase Reference: 6-methylsulfanyl-9-(oxan-2-yl)purine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methylsulfanyl-9-(oxan-2-yl)purine(13153-63-4)
• EPA Substance Registry System: 6-methylsulfanyl-9-(oxan-2-yl)purine(13153-63-4)

Safety Data

• Hazardous Substances Data: 13153-63-4(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 83, p. 2574, 1961 DOI: 10.1021/ja01472a034

InChI:InChI=1/C11H14N4OS/c1-17-11-9-10(12-6-13-11)15(7-14-9)8-4-2-3-5-16-8/h6-8H,2-5H2,1H3

Upstream product

• 7306-68-5 6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 
• 616-38-6 carbonic acid dimethyl ester 
• 110-87-2 3,4-dihydro-2H-pyran 
• 50-66-8 6-methylthiopurine 

Downstream Products

• 66782-10-3 tri-O-benzoyl-1-(6-methylsulfanyl-purin-9-yl)-β-D-1-deoxy-ribofuranose 

Relevant articles and documents

Methyl aryl thioether compound, and synthetic method and applications thereof

The invention discloses a methyl aryl thioether compound represented by formula 2, and a synthetic method and applications thereof. According to the synthetic method, in a reaction solvent, an aryl halide or an aromatic halide, dimethyl carbonate, and potassium thioacetate are taken as reaction raw materials, reaction is carried out in the presence of metal palladium catalyst under the action of a ligand and an alkali so as to obtain the methyl aryl thioether compound. The reaction conditions of the synthetic method are mild; the raw materials are cheap and easily available; reaction operation is simple; yield is relatively high. The methyl aryl thioether compound can be used for providing skeleton structures for the synthesis of a plurality of natural products and medicines, and can be widely applied in industrialized large-scale production.