1315331-49-7Relevant academic research and scientific papers
Tandem isomerization-Mannich reactions from allylic alcohols and their use for the preparation of four diastereoisomers of 1-amino-2-methyl-1-phenyloctan- 3-ol
Cao, Hai T.,Roisnel, Thierry,Gree, Rene
, p. 507 - 510 (2009)
The tandem isomerization-Mannich reaction of octen-3-ol and benzylidene N-sulfonyl imine affords the corresponding β-aminoketones in good yields. Diastereoselective reduction, followed by the deprotection of the primary amine, gives the expected 1-amino-2
A tandem isomerization-Mannich reaction for the enantioselective synthesis of β-amino ketones and β-amino alcohols with applications as key intermediates for ent-nikkomycins and ent-funebrine
Cao, Hai Thuong,Roisnel, Thierry,Valleix, Alain,Gree, Rene
, p. 3430 - 3436 (2011/09/15)
β-Amino ketones, with a primary amino group, are easily obtained in good yields and excellent enantioselectivities through a short sequence that involves, as a key step, a tandem isomerization-Mannich reaction from allylic alcohols with N-tert-butanesulfi
